This issue of Radiologic Clinics of North America focuses on Imaging of Disorders Spanning the Spectrum from Childhood into Adulthood, and is edited by Dr. Edward Y. Lee. Articles will include: Brain Malformations at All Ages: From Aunt Minnie to Zebras for General Radiologists; Cystic Fibrosis from Childhood to Adulthood: What is New in Imaging Assessment; Interstitial Lung Diseases in Adolescent and Young Adults: Different from Older Patients; Repaired Congenital Heart Disease in Older Children and Adults: Up-to-Date Practical Assessment and Characteristic Imaging Findings; Imaging Assessment of Complications from Transplantation from Pediatric to Adult Patients: Part 1 – Solid Organ Transplantation; Imaging Assessment of Complications from Transplantation from Pediatric to Adult Patients: Part 2 – Hematopoietic Stem Cell Transplantation; Beyond Crohn’s Disease: Current Role of Radiologist in Diagnostic Imaging Assessment of Inflammatory Bowel Disease Transitioning from Pediatric to Adult Patients; Imaging Manifestations of Childhood Musculoskeletal Disorders in Adults: Spectrum of Expected to Surprising Findings for General Radiologists; Genetic Syndromes Affecting Both Children and Adults: A Practical Guide to Imaging Based Diagnosis and Management; Spectrum of Imaging Manifestations of Vascular Tumors and Malformations Beyond Childhood: What General Radiologists Need to Know; Congenital Incidental Findings in Children That Can be Mistaken as True Pathologies in Adults: Pearls and Pitfalls of Imaging Diagnosis; and more!